Proposed study
PHENO-001
A proposed observational study to test whether two institutions can describe adults with stable, one-sided motor impairment in the same way.
Led by NeuroCura, founded by Nigel Marsh, MBA
- StatusProposedNot underway
- DesignObservationalNo intervention is described
- ReviewNot soughtNo research ethics approval has been sought or obtained.
- RecruitmentNot enrollingNo participants are sought
What the concept would ask
The initial population in view is adults with cerebral palsy or stable early-acquired neurological injury. Broader comparisons would need their own justification. The aim is a shared description, not a treatment assignment.
Domains a future protocol might define, none of which are being collected here:
- Timing and nature of the injury, and whether the deficit is stable.
- Imaging features, only where an approved protocol calls for them.
- Physiology measures, only where a site already has a lawful way to obtain them.
- Function: limb use, gait, sensation, participation.
- Rehabilitation already received, as history, not as a new prescription.
What it is not
- No treatment of any kind: no focused ultrasound, drug, biologic or cellular product.
- Not recruiting, and not medical advice.
- No access to or copy of hospital record systems.
Questions for a prospective clinical lead
We’re asking surgeons and clinician-scientists to test the idea and tell us what’s missing.
- Which adult group and which daily-life outcomes would make a first study worth doing?
- Which clinical and imaging features could actually be compared across sites?
- Who would sponsor a feasibility review, including ethics and privacy?
- What result should stop the idea, as well as what result should continue it?